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Analysis and interpretation of recurrent and non-recurrent abnormalities associated with acute lymphoblastic leukaemia: online G-banded analysis with supplementary tests as applicable and/or DNA for whole genome copy number changes and structural rearrangements.
EQA INFORMATION
EQA Code
HALL
Submission
Clinical Report
Techniques
Array, Fluorescent In Situ Hybridisation (FISH), Karyotyping, Next Generation Sequencing (NGS)
Enrolled participants will receive details by email when an EQA is open for assessment and/or samples have been dispatched.
Participants are expected to access the instructions and information for the cases/samples online and to analyse them according to their laboratory/centre protocols.
Participants must submit their anonymised results by the deadline using their standard laboratory report or a proforma provided by GenQA. The submitted results are independently assessed for the accuracy of the analytical/genotyping results, clinical interpretation of the results (if appropriate) and clerical accuracy (including report layout and content).
What can I expect as a participant?
Every participant will receive:
An Individual Laboratory/Centre Report (ILR/ICR) with educational advice for each distribution of this EQA.
The Summary report for each distribution of this EQA which contains information regarding general findings, a summary of methodologies used, common errors, number of participants and benchmarking.
Access to a live Performance Certificate summarising your performance status for all EQAs in which you are enrolled.
Please note: EQA details may be subject to change prior to EQA distribution.
PRODUCTS
Sample type: Images: FISH (Fluorescent In-situ Hybridisation), Images: G-banded chromosomes, DNA in TE buffer
Testing/analysis:
Online G-band chromosome analysis.
Online FISH analysis of interphase nuclei or metaphases.
Array/NGS testing of whole genome copy number changes and structural rearrangements.
Conditions/Gene target(s):
Acute Lymphoblastic Leukaemia (ALL)
We aim to include a variety of tests within each EQA. For this EQA please select the required options at enrolment. In addition, you may opt out of any case if it is outside of your routine laboratory scope, by following the instructions in the EQA Distribution letter.
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