Tissue Assessment of Tumour and Cellularity

Registration for Run 12 is now open. For further information see HERE.

The Tissue-i module is for assessment of tumour and cellularity content of H&E stained formalin fixed paraffin embedded (FFPE) tissue and fresh frozen (FF) tissue samples requiring molecular testing.

The assessment of tumour content and cellularity of the tissue samples is critical to deliver high quality molecular testing. Tissue-i aids in standardising tumour annotation and assessment.

Two assessments are delivered per year, including a selection of tissue types:

Breast	Melanoma
Central nervous system	Paediatric
Gastrointestinal tract	Sarcoma
Gynaecological tract	Thyroid
Lung	Urological tract

Molecular testing of solid tumour requires accurate selection of tumour regions for microdissection to ensure:

Sample quality
Sufficiency of tumour DNA
Precision of test result

Who can participate?

All individuals who perform microdissection of tumour regions. Participation can be either as a laboratory or an individual. This histopathology assessment enables individuals to evidence their competency to select appropriate tissue areas for genomic testing.

What is involved?

For each assessment, participants can choose to assess all or some of the tumour types offered in each assessment. Each tumour type includes five cases with a different clinical case scenario and an associated image. Participants have 6 weeks to mark tumour rich regions for macrodissection for molecular testing, and to assess tumour content and cellularity.

Information for participants:

Once registered, participants will receive:
- Details of the next available assessment
- Full instructions for the assessment
The results are assessment by an international panel of experts

On completion of the assessment:

All participants will receive:

Individual report which summarises their submission
Summary report to enable benchmarking against the expert assessment
Certificate of participation

How do I enrol?

Laboratories or clinical centres can purchase multiple GENie Tissue-i platform annual licences for staff members (costed at £550 for up to 3 users, £110 per additional user).
Individual genomics professionals can invest in their own GENie Tissue-i training for £175 per year.
For individuals assessing cases for the NHS England Genomic Medicine Service, NHS England will fund the participation fees. Please contact your Pathology Lead within your Genomic Laboratory Hub to access the EQA.

For further information please contact us at info@genqa.org