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Preimplantation genetic testing (PGT) of blastomere (FISH)

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PGT for structural chromosomal rearrangements using FISH.

EQA INFORMATION

EQA Code
PGTBF
Submission
Clinical Report
Techniques
Fluorescent In Situ Hybridisation (FISH)
Eligibility
All laboratories worldwide
Language
English, French, German, Italian, Polish, Portuguese, Spanish
EQA Accreditation
EQA accredited to ISO 17043:2010
EQA open

Stage 1: 12 May 2025

Stage 2: 09 June 2025

Testing period
3 weeks for Stage 1; 4 weeks for Stage 2

OTHER INFORMATION

 What are participants required to do?
  • Enrolled participants will receive details by email when an EQA is open for assessment and/or samples have been dispatched.  
  • Participants are expected to access the instructions and information for the cases/samples online and to analyse them according to their laboratory/centre protocols. 
  • Participants must submit their anonymised results by the deadline using their standard laboratory report or a proforma provided by GenQA.  The submitted results are independently assessed for the accuracy of the analytical/genotyping results, clinical interpretation of the results (if appropriate) and clerical accuracy (including report layout and content). 

What can I expect as a participant?
Every participant will receive:
  • An Individual Laboratory/Centre Report (ILR/ICR) with educational advice for each distribution of this EQA.
  • The Summary report for each distribution of this EQA which contains information regarding general findings, a summary of methodologies used, common errors, number of participants and benchmarking. 
  • Access to a live Performance Certificate summarising your performance status for all EQAs in which you are enrolled.

Please note: EQA details may be subject to change prior to EQA distribution.   

PRODUCTS

Sample type: Images: FISH (Fluorescent In-situ Hybridisation)
Testing/analysis: Testing strategy based on case scenario presented and online FISH analysis of interphase nuclei.
Stage 1: Work up of probes for a given rearrangement.
Stage 2: Online analysis blastomere FISH images.
Conditions/Gene target(s): Rearrangements where the likely imbalance is <10Mb
Number of cases: Two

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Preimplantation genetic testing (PGT) of blastomere (FISH)

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